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Writer's picturelucky the biologist

Sex determination

In humans, sex determination is the process that determines the biological sex of an offspring and, as a result, the sexual characteristics that they will develop.

Humans typically develop as either male or female, depending on the combination of sex chromosomes that they inherit from their parents

The process of sex determination begins after fertilization, a process where male and female germ cells fuse to form a zygote, or a single-celled, fertilized egg. Germ cells are those that carry genetic information from parents to offspring during fertilization. Male germ cells are sperm cells and female germ cells are egg cells. When the egg and sperm cells fuse, the zygote divides into multiple cells and later forms an embryo.


The embryo includes a combination of part of each parent’s genetic information, including one sex chromosome from each parent. The combination of sex chromosomes that an embryo inherits from germ cells determines what biological sex it will later develop as




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